An Epidemiological Risk Assessment Of Vibrio Cholera

Vibrio cholera pathogen has inauspicious wellness jeopardies, particularly in developing states in Africa. It is normally found in Marine and fresh H2O dwellers, with its being being favored by hapless sanitation, insecure imbibing H2O and nutrient every bit good as unhygienic life conditions. The pathogen is responsible for transmittal of cholera, an infective disease claiming lives of many people in Africa. Vibrio cholera can easy distribute from one individual to another through sharing contaminated nutrient and H2O. Its harmful effects to human existences consequence to decease if untreated for over 2 hours. This paper looks at epidemiological hazard appraisal for vibrio cholera, discoursing the wellness jeopardies associated with the pathogen in Africa.


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Vibrio Cholera pathogen is responsible for transmittal of cholera, an infective disease estimated to do one-year deceases of 120,000 people worldwide and kill up to 50 % of the population when it occurs in developing states ( Todar, 2009 ) . The pathogen is among the most common pathogens in H2O organic structures worldwide, happening in both marine and fresh H2O dwellers. It is a noninvasive being that affects the little bowels by secernment of an anterotoxin. Vibrio cholera produces cholera toxins, the theoretical account enterotoxins that act on mucosal epithelial tissue to do characteristic diarrhoea of the disease cholera, transmitted to human existences through H2O or nutrient. The pathogen has a comparatively simple growing facto demand that favors its growing in man-made media with glucose as the lone beginning of energy and C. This paper discuses the epidemiological hazard appraisal for vibrio cholera in Africa continent ( Ashish, Steven, Wright & A ; Perlin, 2007 ) .

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Statement of Purpose

Vibrio cholera has remained a serious wellness jeopardy in Sub- Saharan Africa, claiming lives of 1000s of hapless people infected yearly.

Epidemiologic Risk Assessment for Vibrio Cholera in Sub- Sahara Africa

World Health Organization ( 1999 ) classifies cholera as one of the most quickly known fatal diseases in Africa, whereby a healthy individual may go hypertensive within one hr after the symptoms start attesting and decease within 2- 3 hours if he goes untreated. The disease moves from the first liquid stool to stock within four to twelve hours, ensuing to decease in 18 hours to several yearss. Furthermore, statistics indicate that Sub- Saharan Africa has the highest reported cholera incidences and mortality rates in the universe, with estimated 108, 535 cholera instances reported yearly, which is more than 3 times the figure in the remainder of the universe combined. In the twelvemonth 1996, 6216 cholera related deceases were reported in Africa, accounting for 93 per centum of all reported cholera deceases worldwide ( World Health Organization, 1999 ) .

Research has shown that the being of the pathogen vibrio cholera is normally favored by unequal environmental direction accelerated by absence of safe imbibing H2O and hapless sanitation. Cholera is hence a disease associated with hapless sanitation, whose epidemics in Africa are linked to ingestion of nutrient and H2O from insecure beginnings such as lakes and rivers. The high hazard countries associated with vibrio cholera are chiefly the peri- urban slums that lack basic substructure, cantonments for refugees and internally displaced people that do non run into minimal demands of clean H2O and sanitation. By and large, most states in Africa are at a high hazard of vibrio cholera infections and deceases due to hapless sanitation, deficiency of safe clean imbibing H2O, poorness, hapless substructure and unequal medical installations ( Todar, 2009 ) .

Hazards associated With Vibrio Cholera

Harmonizing to Finch, Morris, Kaviti, Kagwanja & A ; Levine ( 1988 ) , vibrio cholera causes rapid desiccation, purging, circulatory prostration and decease, with the septic individual losing gallons of protein- free fluid associated with electrolytes, hydrogen carbonates and ions within a short period of clip. This is due to presence of cholera enterotoxin, that activates adenylate cyclase enzyme situated within the cells in the bowels. This activity converts enteric cells into pumps which in bend take electrolyte and H2O from patientaa‚¬a„?s tissues and blood, pumping it into the lms of the bowel.

Todar ( 2009 ) further explains that the inordinate loss of fluid caused by vibrio cholera leads to desiccation, anuresis, acidoisis and daze to the individual infected. Furthermore, vibrio cholera causes watery diarrhoea that contains epithelial cells, flakes of mucous secretion and contains 1000000s of vibrios. This makes the spread of cholera from one individual to another rather easy, therefore the disease is contagious.

The pathogen causes loss of K ions to the patient, a status that may ensue to cardiac complications and circulative failure in patients. Furthermore, untreated cholera often consequences in high mortality rates, runing from 50 to 60 per centum ( Todar, 2009 ) .


In decision, vibrio cholera is a serious wellness jeopardy in Africa and has claimed lives of many people. While it may non be possible to harmonise the inequalities between the rich and the hapless, the overwhelming and lay waste toing life styles of the hapless in developing states allow for the continuity of much poorness related flagellums that account for high degrees of morbidity and mortality such as cholera.

This calls for research workers and other organisations to work together and come up with permanent solutions to extinguish vibrio cholera from the developing states and make healthy lives for the present and future coevalss.

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